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ACS Division of Analytical Chemistry
Theory and Practice of Fast LC
Tuesday, March 4, 2008
1:30 p.m., Room 243 

Organizer:

Jose M Cintron, Eli Lilly & Co

Speakers:

1:30     Leveraging New Chromatographic Technologies to Improve Efficiency in Analytical Development     JOSE M CINTRON, Eli Lilly and Company

1:50     Revisiting the Trade-offs between Speed and Resolution in Modern HPLC: What Particle Size and Column Length Should Be Used  BRIAN A BIDLINGMEYER, Agilent Technologies, Trayton B White, Robert D Ricker

2:10     UHPLC for Pharmaceutical Analyses  MICHAEL SWARTZ, Synomics Pharma

2:30     Fast LC Using Columns Packed with Small Particles  LUIS A COLON, University at Buffalo, Richard W Brice

2:50     Recess

3:05     Fast LC Method Development Using Sub-2-Micron Particles:  Practical Considerations for Pharmaceutical Analysis  ANTON D JERKOVICH, Novartis Pharmaceuticals, Alexey A Makarov, Rosario LoBrutto

3:25     The Role of Efficiency and Selectivity in Small Particle Based LC Separations  FRANK L DORMAN, Restek Corporation, Randy Romesberg, Bruce Albright, Larry Peters, Richard Lake, Rebecca E Wittrig

3:45     Investigating Thermal and Instrumental Influences on Sub 3 µm Columns  JASON A ANSPACH, Phenomenex, Gareth Friedlander, Graham Osborn, Peter C Rahn

Overview:

Faster and more cost efficient analytical techniques are constantly sought out in attempt to meet the current demands to do more with less.  In many industries, such as those related to pharmaceuticals, high performance liquid Chromatography (HPLC) is perhaps the most widely used analytical technique and can be viewed as a major bottleneck in the scheme of sample and information flow.  Thus, HPLC methods that are not only faster but more efficient are highly desired.  This effort has manifested itself towards the use of new HPLC column and instrument technologies.  In this session, gains and challenges involved in implementing such technologies will be discussed by representatives from academia and industry.  They will share their expertise from both a fundamental and practical perspective on the topic.